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The binding of [3H]tamoxifen ([3H]Tam), a nonsteroidal antiestrogen, and of 4-[ 3H]hydroxytamoxifen ([3H]OH-Tam), a metabolite accumulated in vivo in target ...
Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer. Michalides R, Griekspoor A, Balkenende A, ...
Many women with hormone receptor-positive breast cancer will receive tamoxifen at some point in their treatment course. Tamoxifen is biotransformed to the ...
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Tamoxifen Preparation. Materials: • Tamoxifen (SIGMA: T-5648). • Corn oil ( SIGMA: C-8267). • 37° C incubator. • 42° C incubator. • Rocker. • Vortexer ...
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